InVivo Therapeutics (NASDAQ: NVIV) is biomaterial and medical device company focused on the treatment of spinal cord injuries. The company is developing a Neuro-Spinal Scaffold™ (NSS), a biocompatible polylactic-co-glycolic acid (PGLA) and poly-L-lysine (PLL) polymer scaffold that is designed for implantation at the site of the injury. The NSS provides structural support to the spared spinal tissue and a supportive matrix to facilitate endogenous repair processes as it degrades over several weeks.
InVivo is testing the NSS in a human clinical study called INSPIRE (InVivo Study of Probable Benefit of the Neuro-Spinal Scaffold™ for Safety and Neurologic Recovery in Subjects with Complete Thoracic AIS A Spinal Cord Injury). INSPIRE is designed as a 20-patient pivotal study to be used to support market approval under a Humanitarian Device Exemption (HDE) in the U.S. This is a landmark study, and one with significant importance to the company. To get an update on INSPIRE and provide additional information for investors on the future development plans with NSS and beyond, I spoke with InVivo's Chairman and CEO, Mark Perrin.
Below is a transcript of our interview: